Microscopy & Imaging · 2025
Teach your microscope how to print: low-cost and rapid-iteration microfabrication for biology
Our protocol drastically reduces material costs compared to conventional methods and enables design-to-device turnaround within a day. By leveraging open-source microscope control software and existing lab equipment, our workflow lowers the entry barrier to microfabrication, enabling labs to prototype custom solutions for diverse experimental needs while maintaining compatibility with soft lithography and downstream biological assays.
Performance the paper reports
0 of 5- Motion—Motion accuracy: not reported
- Volume—Volumetric accuracy: not reported
- Viability—Cell viability: not reported
- Unattended—Unattended operation: not reported
- Standard—Standard compliance: not reported
The full text was read and states no figure for any of the five.
How hard this is to adopt
4.0 of 5, higher is easierEach score is shown against the range the other 59 builds actually occupy, because no criterion uses the full 1–5 scale. These describe how reproducible the build is, not how good the science is.
Resolution
5/1–5Smallest feature/positioning evidence about 1 µm.
Throughput
4/2–5Evidence of parallel, plate-scale, multi-head, or unattended operation.
Parts sourcing
4/2–4Mostly off-the-shelf or kit-based components.
Skill needed
4/2–4Build/operation described as low-skill or basic assembly.
Facilities needed
4/2–4Uses common benchtop/desktop equipment or generic consumables.
Documentation
3/2–5Some open documentation or files are available.
Validation effort
4/2–4Validation includes standards, benchmarking, replicates, or multi-condition tests.
Cycle time
4/1–4Speed evidence suggests rapid, real-time, or automated operation.
2 further criteria are recorded but not shown
- Application Level — scored 4 (75% of records share one value), so it cannot separate one build from another.
- Build Time — scored 5 (scored for only 6 of 60 records), so it cannot separate one build from another.
Both remain in the published dataset.
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Record metadata
Publication data
Matched by doi · retrieved 2026-07-21
Abstract
. Our protocol drastically reduces material costs compared to conventional methods and enables design-to-device turnaround within a day. By leveraging open-source microscope control software and existing lab equipment, our workflow lowers the entry barrier to microfabrication, enabling labs to prototype custom solutions for diverse experimental needs while maintaining compatibility with soft lithography and downstream biological assays.
Bibliographic details
Access and metrics
Topics and keywords
Funding
- University of Bern · Open Round 2022-4
- Uniscientia Foundation · 187-2021
- Novartis Stiftung für Medizinisch-Biologische Forschung · #20C219
- Experiment · 10.18258/50706
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung · 310030_185376
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung · 310030_207475
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung · CRSII5_183550
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung · PCEFP3_181204
Perspective and practical signals
Why it matters
No narrative note curated yet.
Limitations
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