Microscopy & ImagingMicroscopy and imagingSupplemental record

Developing the OpenFlexure Microscope towards medical use: technical and social challenges of developing globally accessible hardware for healthcare

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Abstract

The OpenFlexure Microscope is an accessible, three-dimensional-printed robotic microscope, with sufficient image quality to resolve diagnostic features including parasites and cancerous cells. As access to lab-grade microscopes is a major challenge in global healthcare, the OpenFlexure Microscope has been developed to be manufactured, maintained and used in remote environments, supporting point-of-care diagnosis. The steps taken in transforming the hardware and software from an academic prototype towards an accepted medical device include addressing technical and social challenges, and are key for any innovation targeting improved effectiveness in low-resource healthcare. This article is part of the Theo Murphy meeting issue 'Open, reproducible hardware for microscopy'.

Bibliographic details

Published
2024-06-03
Journal/source
Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences
Publisher
The Royal Society
DOI
10.1098/rsta.2023.0257
Type
journal-article
Language
en
Volume / issue
382 / 2274
Pages
Not supplied
ISSN
1364-503X, 1471-2962

Access and metrics

Open access
Yes
OA status
hybrid
License
cc-by
Version
publishedVersion
Cited by
7
References
16
Retracted
No

Authors and affiliations

  1. Joe KnapperCorresponding authorUniversity of Glasgow
  2. Freya WhitefordUniversity of Glasgow
  3. Daniel RosenBaylor College of Medicine
  4. W. J. WadsworthUniversity of Bath
  5. Julian Stirling
  6. Catherine MkindiIfakara Health Institute
  7. Joram MdudaIfakara Health Institute
  8. Valerian L. Sanga
  9. Paul T. Nyakyi
  10. Thomas Hervé Mboa Nkoudou
  11. Élisée Jafsia
  12. Stéphane Fadanka
  13. K HummelThe University of Texas MD Anderson Cancer Center
  14. Sharmila AnandasabapathyBaylor College of Medicine
  15. Richard BowmanUniversity of Glasgow

Topics and keywords

Biomedical and Engineering EducationArtificial Intelligence in Healthcare and EducationScientific Computing and Data ManagementMicroscopeHealth carePoint of careComputer scienceSoftwareKey (lock)Resource (disambiguation)NanotechnologyBusinessMultimediaMedicineComputer security

Funding

  • Royal Society · RGF\EA\181034