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MicrofabricationMicroscopy & ImagingMicroscopy and imagingSupplemental record

Teach your microscope how to print: low-cost and rapid-iteration microfabrication for biology

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Matched by doi · retrieved 2026-07-21

Abstract

. Our protocol drastically reduces material costs compared to conventional methods and enables design-to-device turnaround within a day. By leveraging open-source microscope control software and existing lab equipment, our workflow lowers the entry barrier to microfabrication, enabling labs to prototype custom solutions for diverse experimental needs while maintaining compatibility with soft lithography and downstream biological assays.

Bibliographic details

Published
2025-01-01
Journal/source
Lab on a Chip
Publisher
Royal Society of Chemistry (RSC)
DOI
10.1039/d5lc00181a
Type
journal-article
Language
en
Volume / issue
25 / 16
Pages
4091-4105
ISSN
1473-0197, 1473-0189

Access and metrics

Open access
Yes
OA status
hybrid
License
cc-by
Version
publishedVersion
Cited by
4
References
63
Retracted
No
Open-access landing page

Authors and affiliations

  1. Lucien HinderlingCorresponding authorUniversity of Bern
  2. Remo HadornUniversity of Bern
  3. Moritz KwasnyUniversity of Bern
  4. Joël FreiUniversity of Bern
  5. Benjamin GrädelUniversity of Bern
  6. Sacha PsalmonUniversity of Bern
  7. Yannick BlumUniversity of Bern
  8. Rémi BerthozInstitut de génétique et de biologie moléculaire et cellulaire
  9. Alex E. LandoltUniversity of Bern
  10. Benjamin D. TowbinUniversity of Bern
  11. Daniel RivelineCentre National de la Recherche Scientifique · Institut de génétique et de biologie moléculaire et cellulaire · Université de Strasbourg
  12. Olivier PertzCorresponding authorUniversity of Bern

Topics and keywords

Microfluidic and Bio-sensing TechnologiesNanofabrication and Lithography Techniques3D Printing in Biomedical ResearchMicrofabricationPhotolithographyMicroscopeNanotechnologyRepurposingFluorescence microscopeMicrofluidicsMaterials scienceComputer scienceEngineeringOpticsFluorescence

Funding

  • University of Bern · Open Round 2022-4
  • Uniscientia Foundation · 187-2021
  • Novartis Stiftung für Medizinisch-Biologische Forschung · #20C219
  • Experiment · 10.18258/50706
  • Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung · 310030_185376
  • Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung · 310030_207475
  • Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung · CRSII5_183550
  • Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung · PCEFP3_181204