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Bioprinting · Extrusion · Microextrusion bioprinter · 2023 · Frontiers in Bioengineering and Biotechnology

Development and implementation of a significantly low-cost 3D bioprinter using recycled scrap material

Low-cost 3D bioprinter built from recycled scrap metal and off-the-shelf electronics; no 3D printer required to build it

Performance the paper reports

1 of 5
  1. Motion10 µmMotion accuracy: reported
  2. Volume—Volumetric accuracy: not reported
  3. Viability—Cell viability: not reported
  4. Unattended—Unattended operation: not reported
  5. Standard—Standard compliance: not reported
  • Motion / positional accuracy10 µm
    [curated metric] Z-axis step resolution of 10 µm; 40 mm/s max non-printing move speed; 2-10 mm/s typical print speed

How hard this is to adopt

3.6 of 5, higher is easier

Each score is shown against the range the other 59 builds actually occupy, because no criterion uses the full 1–5 scale. These describe how reproducible the build is, not how good the science is.

  • Resolution

    not scored

    no clear evidence of printing resolution

  • Throughput

    2/2–5

    Operation appears single-unit or manually constrained.

  • Parts sourcing

    4/2–4

    Mostly off-the-shelf or kit-based components.

  • Skill needed

    4/2–4

    Build/operation described as low-skill or basic assembly.

  • Facilities needed

    3/2–4

    Requires accessible but nontrivial lab/maker equipment.

  • Documentation

    4/2–5

    Open resources include several build or operation artifacts.

  • Validation effort

    4/2–4

    Validation includes standards, benchmarking, replicates, or multi-condition tests.

  • Cycle time

    4/1–4

    Speed evidence suggests rapid, real-time, or automated operation.

2 further criteria are recorded but not shown
  • Application Level — scored 2 (75% of records share one value), so it cannot separate one build from another.
  • Build Time (scored for only 6 of 60 records), so it cannot separate one build from another.

Both remain in the published dataset.

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Publication data

Matched by doi · retrieved 2026-07-21

Abstract

The field of 3D bioengineering proposes to effectively contribute to the manufacture of artificial multicellular organ/tissues and the understanding of complex cellular mechanisms. In this regard, 3D cell cultures comprise a promising bioengineering possibility for the alternative treatment of organ function loss, potentially improving patient life expectancies. Patients with end-stage disease, for example, could benefit from treatment until organ transplantation or even undergo organ function restoration. Currently, 3D bioprinters can produce tissues such as trachea cartilage or artificial skin. Most low-cost 3D bioprinters are built from fused deposition modeling 3D printer frames modified for the deposition of biologically compatible material, ranging between $13.000,00 and $300.000,00. Furthermore, the cost of consumables should also be considered as they, can range from $3,85 and $100.000,00 per gram, making biomaterials expensive, hindering bioprinting access. In this context, our report describes the first prototype of a significantly low-cost 3D bioprinter built from recycled scrap metal and off-the-shelf electronics. We demonstrate the functionalized process and methodology proof of concept and aim to test it in different biological tissue scaffolds in the future, using affordable materials and open-source methodologies, thus democratizing the state of the art of this technology.

Bibliographic details

Published
2023-04-07
Journal/source
Frontiers in Bioengineering and Biotechnology
Publisher
Frontiers Media SA
DOI
10.3389/fbioe.2023.1108396
Type
journal-article
Language
en
Volume / issue
11
Pages
Not supplied
ISSN
2296-4185

Access and metrics

Open access
Yes
OA status
gold
License
cc-by
Version
publishedVersion
Cited by
14
References
36
Retracted
No

Authors and affiliations

  1. Jaciara Fernanda Gomes GamaFundação Oswaldo Cruz
  2. Evellyn Araújo DiasFundação Oswaldo Cruz
  3. Rosângela Marques Gonçalves Aguiar CoelhoFundação Oswaldo Cruz
  4. André Maia ChagasUniversity of Sussex · Yobe State University
  5. José Aguiar Coelho NtFundação Oswaldo Cruz
  6. Luiz Anastácio AlvesCorresponding authorFundação Oswaldo Cruz

Topics and keywords

3D Printing in Biomedical ResearchAdditive Manufacturing and 3D Printing TechnologiesInnovative Microfluidic and Catalytic Techniques InnovationContext (archaeology)3D bioprintingNanotechnologyBiomedical engineeringBiochemical engineeringComputer scienceMaterials scienceTissue engineeringEngineering

Funding

  • Fundação Carlos Chagas Filho de Amparo à Pesquisa Do Estado do Rio de Janeiro · 001
Perspective and practical signals

Why it matters

Shows extreme cost-reduction approach; practical for access/democratization discussions.

Limitations

Resolution/precision tradeoffs from using scrap/recycled components; build quality may vary with available scrap materials

Skills needed

Metalworking/scrap fabricationbasic electronics assemblyno 3D printer access required

Democratizing features

can be built from locally-sourced materials (scrap metal), no 3D printer required