Bioprinting · 2024
Development of a microfluidic-assisted open-source 3D bioprinting system (MOS3S) for the engineering of hierarchical tissues
crosslinking and scaffolds fabrication. The coupling of 3D printed syringe pumps with the motion control system is used for driving the tunable extrusion of inks for the fabrication of centimeter scale hierarchical lattice constructs for tissue engineering purposes.
Performance the paper reports
0 of 5- Motion—Motion accuracy: not reported
- Volume—Volumetric accuracy: not reported
- Viability—Cell viability: not reported
- Unattended—Unattended operation: not reported
- Standard—Standard compliance: not reported
The full text was read and states no figure for any of the five.
How hard this is to adopt
3.5 of 5, higher is easierEach score is shown against the range the other 59 builds actually occupy, because no criterion uses the full 1–5 scale. These describe how reproducible the build is, not how good the science is.
Resolution
3/1–5Dispensed 50-280 uL (n=3) with Bland-Altman error growing as volume falls; printing flow rates 10-30 uL/min producing 250 µm strands; no pulsation data.
Throughput
4/2–5Three 3D-printed syringe pumps on separate stepper drivers addressed independently by G-code via DISTINCT_E_FACTORS, with automated ink switching and unattended 20-layer gradient prints.
Parts sourcing
3/2–4Mix of common parts and custom/printed components.
Skill needed
4/2–4Build/operation described as low-skill or basic assembly.
Facilities needed
4/2–4Uses common benchtop/desktop equipment or generic consumables.
Documentation
4/2–5Open resources include several build or operation artifacts.
Validation effort
3/2–4Multiple volumes, six hydrogel formulations, collapse test and strand/pore measurement against design, but no experimental benchmark against a commercial bioprinter or pump.
Cycle time
3/1–4No timing comparison reported; ink transition took 8 min at 20 uL/min and 16 min at 10 uL/min with no conventional reference.
2 further criteria are recorded but not shown
- Application Level — scored 5 (75% of records share one value), so it cannot separate one build from another.
- Build Time (scored for only 6 of 60 records), so it cannot separate one build from another.
Both remain in the published dataset.
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Publication data
Matched by title · retrieved 2026-07-21
Abstract
crosslinking and scaffolds fabrication. The coupling of 3D printed syringe pumps with the motion control system is used for driving the tunable extrusion of inks for the fabrication of centimeter scale hierarchical lattice constructs for tissue engineering purposes. MOS3S performance have been validated to fabricate high-resolution structures with coaxial microfluidic technology, opening to new frontiers for seminal studies in pre-clinical disease modelling and tissue regeneration.
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