Liquid Handling · Automation · Pipetting/dispensing · 2018 · Energies
Analytical Measurements and Efficient Process Generation Using a Dual–Arm Robot Equipped with Electronic Pipettes
The continued growth in life sciences is being accompanied by the constantly rising demand for robotic systems. Today, bioscreening and high–throughput screening processes are well automated.
Performance the paper reports
0 of 5- Motion—Motion accuracy: not reported
- Volume—Volumetric accuracy: not reported
- Viability—Cell viability: not reported
- Unattended—Unattended operation: not reported
- Standard—Standard compliance: not reported
The full text was read and states no figure for any of the five.
How hard this is to adopt
3.1 of 5, higher is easierEach score is shown against the range the other 59 builds actually occupy, because no criterion uses the full 1–5 scale. These describe how reproducible the build is, not how good the science is.
Resolution
4/1–5Electronic pipettes span 5-200 uL and 50-1000 uL, so a 5 uL minimum; 100 uL gave a 95.42 uL mean at 3.79% CV, not sub-uL.
Throughput
3/2–5One pipette on one arm forming a single channel, 12 vials per run; dual-pipette parallel operation is explicitly future work rather than demonstrated.
Parts sourcing
4/2–4Mostly off-the-shelf or kit-based components.
Skill needed
2/2–4Multiple advanced technical skills appear required.
Facilities needed
3/2–4Requires accessible but nontrivial lab/maker equipment.
Documentation
2/2–5Open build documentation is not clearly identified.
Validation effort
4/2–4Gravimetric n=12 at 100 uL and 1300 uL with a direct head-to-head comparison against conventional manual pipettes on the same robot; water only, no drift or carryover testing.
Cycle time
3/1–4Total process 11.1 min with electronic versus 12.2 min with manual pipettes (~9% faster, within +/-20%); per-step pipetting is actually 25 s versus 8 s.
2 further criteria are recorded but not shown
- Application Level — scored 4 (75% of records share one value), so it cannot separate one build from another.
- Build Time (scored for only 6 of 60 records), so it cannot separate one build from another.
Both remain in the published dataset.
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Record metadata
Publication data
Matched by doi · retrieved 2026-07-21
Abstract
The continued growth in life sciences is being accompanied by the constantly rising demand for robotic systems. Today, bioscreening and high–throughput screening processes are well automated. In contrast, a deficit can be found in the area of analytical measurements with complex and frequently changing processes. Robots undertake not only transportation tasks, but also direct sample manipulation and subsequent analytical measurements. Due to their human-like structure, dual-arm robots perform such processes similar to human operation. Liquid handling is required to transfer chemicals, to prepare standard solutions, or to dilute samples. Two electronic pipettes with different volume ranges (5–200 µL and 50–1000 µL) were integrated into a dual–arm robotic system. The main focus in this publication is the software interface for alternating robot and pipette control as well as the high–level process control system. The performance using a dual–arm robot equipped with electronic pipettes and conventional manual pipettes was determined and compared. The automation system presented is the first integration of a dual-arm robot in analytical measurement processes. Conventional manual laboratory pipettes and electronic pipettes are simultaneously used for liquid-handling tasks. The software control system enables a flexible and user-friendly process generation.
Bibliographic details
Access and metrics
Topics and keywords
Funding
- Bundesministerium für Wirtschaft und Energie · FKZ: ZF4066003DB6
Perspective and practical signals
Why it matters
Dual-arm robot using electronic pipettes for liquid handling in analytical workflows.
Limitations
No limitation note curated yet.