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Liquid handling · Automation · Control software · Pipetting/dispensing · OpenLH · 2019 · CHI EA (ACM) | (PDF / conference-style)

OpenLH: Open Liquid-Handling System for Creative Experimentation with Biology

The biological prototyping revolution is in motion, and new tools are needed to empower HCI researchers, designers, makers, and bio-enthusiasts to experiment with live organisms. We present OpenLH, a liquid handling system that empowers users to conduct accurate and repetitive experiments with live biology in a sterile, open, and affordable way.

Performance the paper reports

0 of 5
  1. Motion—Motion accuracy: not reported
  2. Volume—Volumetric accuracy: not reported
  3. Viability—Cell viability: not reported
  4. Unattended—Unattended operation: not reported
  5. Standard—Standard compliance: not reported

The full text was read and states no figure for any of the five.

How hard this is to adopt

3.5 of 5, higher is easier

Each score is shown against the range the other 59 builds actually occupy, because no criterion uses the full 1–5 scale. These describe how reproducible the build is, not how good the science is.

  • Resolution

    4/1–5

    Dispenses 0.2 uL droplets (0.3 uL bioprint) via a linear-actuator syringe, but a 0.15 uL average SD makes true sub-uL reliability marginal.

  • Throughput

    3/2–5

    Single pipette head, stated as a limitation by the authors; automates a 48-well serial dilution with tip changes but handles one channel and fluid at a time.

  • Parts sourcing

    4/2–4

    Mostly off-the-shelf or kit-based components.

  • Skill needed

    4/2–4

    Build/operation described as low-skill or basic assembly.

  • Facilities needed

    4/2–4

    Uses common benchtop/desktop equipment or generic consumables.

  • Documentation

    3/2–5

    Some open documentation or files are available.

  • Validation effort

    3/2–4

    Gravimetric water dispensing across 0.25-15 extruder steps (n=4) with SD reported and a calibration manual supplied; "as accurate as commercial" is asserted but never experimentally benchmarked.

  • Cycle time

    3/1–4

    No timing comparison reported; only a qualitative claim that speed is comparable to human-hand pipetting in a single transaction.

2 further criteria are recorded but not shown
  • Application Level — scored 4 (75% of records share one value), so it cannot separate one build from another.
  • Build Time (scored for only 6 of 60 records), so it cannot separate one build from another.

Both remain in the published dataset.

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Publication data

Matched by doi · retrieved 2026-07-21

Abstract

The biological prototyping revolution is in motion, and new tools are needed to empower HCI researchers, designers, makers, and bio-enthusiasts to experiment with live organisms. We present OpenLH, a liquid handling system that empowers users to conduct accurate and repetitive experiments with live biology in a sterile, open, and affordable way. Full abstract at the publisher

Bibliographic details

Published
2019-03-15
Journal/source
Proceedings of the Thirteenth International Conference on Tangible, Embedded, and Embodied Interaction
Publisher
ACM
DOI
10.1145/3294109.3295619
Type
proceedings-article
Language
en
Volume / issue
Not supplied
Pages
55-64
ISSN
Not supplied

Access and metrics

Open access
No
OA status
closed
License
https://www.acm.org/publications/policies/copyright_policy#Background
Version
publishedVersion
Cited by
48
References
35
Retracted
No

Authors and affiliations

  1. Gilad GomeReichman University
  2. Julian WaksbergReichman University
  3. Andrey GrishkoReichman University
  4. Iddo Yehoshua WaldReichman University
  5. Oren ZuckermanReichman University

Topics and keywords

Cell Image Analysis TechniquesOlfactory and Sensory Function StudiesInnovative Microfluidic and Catalytic Techniques InnovationComputer scienceContext (archaeology)Human–computer interactionMultimedia
Perspective and practical signals

Why it matters

Uses a commercial robotic arm + modified pipette + block-based programming; relevant example of robot-arm liquid handling. | Early ‘open liquid handling’ system description; may provide useful design patterns + references.

Limitations

No limitation note curated yet.