Liquid handling · Automation · Control software · Pipetting/dispensing · OpenLH · 2019 · CHI EA (ACM) | (PDF / conference-style)
OpenLH: Open Liquid-Handling System for Creative Experimentation with Biology
The biological prototyping revolution is in motion, and new tools are needed to empower HCI researchers, designers, makers, and bio-enthusiasts to experiment with live organisms. We present OpenLH, a liquid handling system that empowers users to conduct accurate and repetitive experiments with live biology in a sterile, open, and affordable way.
Performance the paper reports
0 of 5- Motion—Motion accuracy: not reported
- Volume—Volumetric accuracy: not reported
- Viability—Cell viability: not reported
- Unattended—Unattended operation: not reported
- Standard—Standard compliance: not reported
The full text was read and states no figure for any of the five.
How hard this is to adopt
3.5 of 5, higher is easierEach score is shown against the range the other 59 builds actually occupy, because no criterion uses the full 1–5 scale. These describe how reproducible the build is, not how good the science is.
Resolution
4/1–5Dispenses 0.2 uL droplets (0.3 uL bioprint) via a linear-actuator syringe, but a 0.15 uL average SD makes true sub-uL reliability marginal.
Throughput
3/2–5Single pipette head, stated as a limitation by the authors; automates a 48-well serial dilution with tip changes but handles one channel and fluid at a time.
Parts sourcing
4/2–4Mostly off-the-shelf or kit-based components.
Skill needed
4/2–4Build/operation described as low-skill or basic assembly.
Facilities needed
4/2–4Uses common benchtop/desktop equipment or generic consumables.
Documentation
3/2–5Some open documentation or files are available.
Validation effort
3/2–4Gravimetric water dispensing across 0.25-15 extruder steps (n=4) with SD reported and a calibration manual supplied; "as accurate as commercial" is asserted but never experimentally benchmarked.
Cycle time
3/1–4No timing comparison reported; only a qualitative claim that speed is comparable to human-hand pipetting in a single transaction.
2 further criteria are recorded but not shown
- Application Level — scored 4 (75% of records share one value), so it cannot separate one build from another.
- Build Time (scored for only 6 of 60 records), so it cannot separate one build from another.
Both remain in the published dataset.
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Report what it took, including attempts that stalled. A failed build tells the next laboratory what the documentation leaves out.
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The index has no licence on the design files or which files exist (CAD, bill of materials, firmware…) for this build. If you are an author or have built it, you know; a GitHub issue pre-filled with this record takes a minute.
Record metadata
Publication data
Matched by doi · retrieved 2026-07-21
Abstract
The biological prototyping revolution is in motion, and new tools are needed to empower HCI researchers, designers, makers, and bio-enthusiasts to experiment with live organisms. We present OpenLH, a liquid handling system that empowers users to conduct accurate and repetitive experiments with live biology in a sterile, open, and affordable way. Full abstract at the publisher
Bibliographic details
Access and metrics
Topics and keywords
Perspective and practical signals
Why it matters
Uses a commercial robotic arm + modified pipette + block-based programming; relevant example of robot-arm liquid handling. | Early ‘open liquid handling’ system description; may provide useful design patterns + references.
Limitations
No limitation note curated yet.