Liquid HandlingBioprintingExtrusionCurated metadata

A hackable, multi-functional, and modular extrusion 3D printer for soft materials

Useful adjacent open platform for hydrogel/soft-matter printing; may be bioprinting-enabling.

Open-sourcemedium skillmoderate docsCrossrefOpenAlex
Publication data

Crossref and OpenAlex

Publication record

Matched by title · retrieved 2026-07-21

Abstract

Three-dimensional (3D) printing has emerged as a powerful tool for material, food, and life science research and development, where the technology's democratization necessitates the advancement of open-source platforms. Herein, we developed a hackable, multi-functional, and modular extrusion 3D printer for soft materials, nicknamed Printer.HM. Multi-printhead modules are established based on a robotic arm for heterogeneous construct creation, where ink printability can be tuned by accessories such as heating and UV modules. Software associated with Printer.HM were designed to accept geometry inputs including computer-aided design models, coordinates, equations, and pictures, to create prints of distinct characteristics. Printer.HM could further perform versatile operations, such as liquid dispensing, non-planar printing, and pick-and-place of meso-objects. By 'mix-and-match' software and hardware settings, Printer.HM demonstrated printing of pH-responsive soft actuators, plant-based functional hydrogels, and organ macro-anatomical models. Integrating affordability and open design, Printer.HM is envisaged to democratize 3D printing for soft, biological, and sustainable material architectures.

Bibliographic details

Published
2022-07-19
Journal/source
Scientific Reports
Publisher
Springer Science and Business Media LLC
DOI
10.1038/s41598-022-16008-6
Type
journal-article
Language
en
Volume / issue
12 / 1
Pages
Not supplied
ISSN
2045-2322

Access and metrics

Open access
Yes
OA status
gold
License
cc-by
Version
publishedVersion
Cited by
32
References
37
Retracted
No

Authors and affiliations

  1. Iek Man LeiUniversity of Cambridge
  2. Yaqi ShengUniversity of Cambridge
  3. Chon Lok LeiUniversity of Macau · University of Oxford
  4. Cillian LeowUniversity of Cambridge
  5. Yan Yan Shery HuangCorresponding authorUniversity of Cambridge

Topics and keywords

Additive Manufacturing and 3D Printing Technologies3D Printing in Biomedical ResearchModular Robots and Swarm IntelligenceModular designExtrusionComputer scienceMaterials scienceComposite materialProgramming language

Funding

  • European Research Council · ERC-StG, 758865
  • W.D Armstrong Trust Fund
  • Chinese Government Scholarship